CA102

CA102 is an oncolytic adenovirus* that expresses a bi-specific shRNA** to knock-down mTOR and STAT3 oncogenes, which are known to be involved in cancer growth and survival. Target diseases are bladder cancer and pancreatic cancer.

*Oncolytic adenovirus: Engineered adenovirus to infect, replicate, and kill only cancer cells

**Bi-specific shRNA: Modified bi-specific siRNA to a short-hairpin (sh) structure which can be expressed by a single promoter