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Naked siRNA

Curigin is improving the biophysical properties of siRNA for stable and efficient disease-associated gene knockdown.

Naked siRNA can maintain stability in the human body by chemically modifying the original nucleotide sequences, and it is possible to improve endocytosis and knockdown efficiency through such modifications.

By applying Curigin’s bispecific shRNA technology, we can simultaneously target and suppress two or more key genes through appropriate stabilizing modifications.